Vitamin D Receptor Activation Mitigates the Impact of Uremia on Endothelial Function in the 5/6 Nephrectomized Rats

Ruth Wu-Wong, J.; T. Noonan, William; Nakane, Masaki; A. Brooks, Kristin; A. Segreti, Jason; S. Polakowski, James; F. Cox, Bryan

doi:10.1155/2010/625852

Public

Vitamin D Receptor Activation Mitigates the Impact of Uremia on Endothelial Function in the 5/6 Nephrectomized Rats

Published in International Journal of Endocrinology • Jan 1, 2010

Authors:

J. Ruth Wu-Wong

William T. Noonan

Masaki Nakane

Abstract

Endothelial dysfunction increases cardiovascular disease risk in chronic kidney disease (CKD). This study investigates whether VDR activation affects endothelial function in CKD. The 5/6 nephrectomized (NX) rats with experimental chronic renal insufficiency were treated with or without paricalcitol,...

Subject

Paricalcitol

Medicine

Endocrinology

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