Detection of 14‐3‐3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt‐Jakob disease

Zerr, Inga; Bodemer, Monika; Gefeller, Olaf; Otto, Markus; Poser, S.; Wiltfang, Jens; Windl, Otto; A. Kretzschmar, Hans; Weber, Thomas

doi:10.1002/ana.410430109

Public

Detection of 14‐3‐3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt‐Jakob disease

Published in Annals of Neurology • Jan 1, 1998

Authors:

Inga Zerr

Monika Bodemer

Olaf Gefeller

Abstract

The analysis of 14-3-3 protein in cerebrospinal fluid (CSF) was shown to be highly sensitive and specific for the diagnosis of Creutzfeldt-Jakob disease (CJD). However, the predictive value of this test in the clinical diagnosis of, and its relation to, sporadic, genetic, and iatrogenic CJD cases ha...

Subject

Cerebrospinal fluid

Medicine

Encephalitis

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