<scp>CD</scp>64 distinguishes macrophages from dendritic cells in the gut and reveals the <scp>T</scp>h1‐inducing role of mesenteric lymph node macrophages during colitis

Tamoutounour, Samira; Henri, Sandrine; Lelouard, Hugues; de Bovis, Béatrice; de Haar, Colin; Janneke van der Woude, C.; M. Woltman, Andrea; Reyal, Yasmin; Bonnet, Dominique; Sichien, Dorine; C. Bain, Calum; McI. Mowat, Allan; Reis e Sousa, Caetano; Franz Poulin, Lionel; MALISSEN, Bernard; Guilliams, Martin

doi:10.1002/eji.201242847

Public

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1‐inducing role of mesenteric lymph node macrophages during colitis

Published in European Journal of Immunology • Aug 31, 2012

Authors:

Samira Tamoutounour

Sandrine Henri

Hugues Lelouard

Abstract

Dendritic cells (DCs) and monocyte-derived macrophages (MΦs) are key components of intestinal immunity. However, the lack of surface markers differentiating MΦs from DCs has hampered understanding of their respective functions. Here, we demonstrate that, using CD64 expression, MΦs can be distinguish...

Subject

Biology

Lymph node

Immunology

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