Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1

Risch, Angela; Ramroth, Heribert; Raedts, Vivianne; Rajaee‐Behbahani, Nahid; Schmezer, Peter; Bartsch, Helmut; Becher, Heiko; Dietz, Andreas

doi:10.1097/00008571-200304000-00007

Public

Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1

Published in Pharmacogenetics • Apr 1, 2003

Authors:

Angela Risch

Heribert Ramroth

Vivianne Raedts

Abstract

OBJECTIVE: Alcohol and tobacco consumption are recognized risk factors for upper aerodigestive tract tumours, however individual susceptibility to these environmental factors varies. As part of the Rhein-Neckar Larynx-case-control study, this study investigated the potential risk-modifying effect of...

Subject

Genotype

ADH1B

Population

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