Genetic and epigenetic analysis of recurrent hydatidiform mole.

BE, Hayward; Vos M, De; N, Talati; MR, Abdollahi; GR, Taylor; E, Meyer; D, Williams; ER, Maher; F, Setna; K, Nazir; S, Hussaini; H, Jafri; Y, Rashid; E, Sheridan; DT, Bonthron

doi:10.1002/humu.20993

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Genetic and epigenetic analysis of recurrent hydatidiform mole.

Shared by NobleBlocks on May 1, 2009 • 12:00 AM UTC

Authors:

Hayward BE

De Vos M

Talati N

Abstract

Familial biparental hydatidiform mole (FBHM) is a maternal-effect autosomal recessive disorder in which recurrent pregnancy failure with molar degeneration occurs. The phenotype mimics molar pregnancy due to androgenesis, despite the normal genetic makeup of the conceptus. FBHM appears to result fro...

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