Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells

Yang, Ying; Li, Shuping; Yang, Qiao; Shi, Yu; Zheng, Min; Liu, Yanning; Chen, Feng; Song, Guangzhong; Xu, Hangdi; Wan, Tianhong; He, Jiliang; Chen, Zhi

doi:10.1159/000358696

Public

Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells

Published in Cellular Physiology and Biochemistry • Jan 1, 2014

Authors:

Ying Yang

Shuping Li

Qiao Yang

Abstract

BACKGROUND: Resveratrol (Res) is a polyphenol anti-inflammatory agent. We have studied the link between the anti-inflammatory effects of Res and the high mobility group box 1(HMGB1) signaling pathway. METHODS: Murine macrophage-like RAW264.7 cells (RAW264.7 cells) were either untreated (control) or ...

Subject

HMGB1

Proinflammatory cytokine

TLR4

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