Resveratrol reduces the proinflammatory effects and lipopolysaccharide- induced expression of HMGB1 and TLR4 in RAW264.7 cells.

Y, Yang; S, Li; Q, Yang; Y, Shi; M, Zheng; Y, Liu; F, Chen; G, Song; H, Xu; T, Wan; J, He; Z, Chen

doi:10.1159/000358696

Public

Resveratrol reduces the proinflammatory effects and lipopolysaccharide- induced expression of HMGB1 and TLR4 in RAW264.7 cells.

Shared by NobleBlocks on Apr 28, 2014 • 12:00 AM UTC

Authors:

Yang Y

Li S

Yang Q

Abstract

Background Resveratrol (Res) is a polyphenol anti-inflammatory agent. We have studied the link between the anti-inflammatory effects of Res and the high mobility group box 1(HMGB1) signaling pathway.Methods Murine macrophage-like RAW264.7 cells (RAW264.7 cells) were either untreated (control) or tre...

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