Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Published in Proceedings of the National Academy of Sciences of the United States of America • Sep 3, 1996
Authors:,,
J G Herman
J R Graff
S Myöhänen
Abstract
Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes such as the regulation of imprinted genes, X chromosome inactivation, and tumor suppressor gene silencing in human cancer. We describe a new method, MSP (methylation-specifi...
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