A Study to Evaluate Safety and Efficacy of Mepolizumab in Patients with Moderate Persistent Asthma

Flood-Page, Patrick; A. Swenson, Cheri; Faiferman, Isidore; G. Matthews, John; Williams, Michael; Brannick, Lesley; S. Robinson, Douglas; E. Wenzel, Sally; W. Busse, William; T. Hansel, Trevor; Barnes, Neil

doi:10.1164/rccm.200701-085oc

Public

A Study to Evaluate Safety and Efficacy of Mepolizumab in Patients with Moderate Persistent Asthma

Published in American Journal of Respiratory and Critical Care Medicine • Sep 13, 2007

Authors:

Patrick Flood-Page

Cheri A. Swenson

Isidore Faiferman

Abstract

RATIONALE: Accumulation of eosinophils in the bronchial mucosa of individuals with asthma is considered to be a central event in the pathogenesis of asthma. In animal models, airway eosinophil recruitment and airway hyperresponsiveness in response to allergen challenge are reduced by specific target...

Subject

Mepolizumab

Medicine

Asthma

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!