Association of Cystic Fibrosis with Abnormalities in Fatty Acid Metabolism

D. Freedman, Steven; G. Blanco, Paola; M. Zaman, Munir; C. Shea, Julie; Ollero, Mario; K. Hopper, Isabel; Weed, Deborah; Gelrud, Andrés; M. Regan, Meredith; Laposata, Michael; G. Álvarez, Juan; O’Sullivan, Brian

doi:10.1056/nejmoa021218

Public

Association of Cystic Fibrosis with Abnormalities in Fatty Acid Metabolism

Published in New England Journal of Medicine • Feb 4, 2004

Authors:

Steven D. Freedman

Paola G. Blanco

Munir M. Zaman

Abstract

BACKGROUND: Patients with cystic fibrosis have altered levels of plasma fatty acids. We previously demonstrated that arachidonic acid levels are increased and docosahexaenoic acid levels are decreased in affected tissues from cystic fibrosis-knockout mice. In this study we determined whether humans ...

Subject

Cystic fibrosis

Docosahexaenoic acid

Arachidonic acid

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