GPI-anchored cell-surface molecules complexed to protein tyrosine kinases.

I, Stefanová; V, Horejsí; IJ, Ansotegui; W, Knapp; H, Stockinger

doi:10.1126/science.1719635

Public

GPI-anchored cell-surface molecules complexed to protein tyrosine kinases.

Shared by NobleBlocks on Nov 1, 1991 • 12:00 AM UTC

Authors:

Stefanová I

Horejsí V

Ansotegui IJ

Abstract

Binding of ligand or antibody to certain cell-surface proteins that are anchored to the membrane by glycophosphatidylinositol (GPI) can cause activation of leukocytes. However, it is not known how these molecules, which lack intracellular domains, can transduce signals. The GPI-linked human molecule...

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