Merkel cell carcinoma can be distinguished from metastatic small cell carcinoma using antibodies to cytokeratin 20 and thyroid transcription factor 1

Leech, Sue; J O Kolar, A; Barrett, Paul; Sinclair, Shelley; Leonard, N.

doi:10.1136/jcp.54.9.727

Public

Merkel cell carcinoma can be distinguished from metastatic small cell carcinoma using antibodies to cytokeratin 20 and thyroid transcription factor 1

Published in Journal of Clinical Pathology • Sep 1, 2001

Authors:

Sue Leech

A J O Kolar

Paul Barrett

Abstract

AIM: To investigate whether immunohistochemical staining for cytokeratin 20 (CK20) and thyroid transcription factor 1 (TTF-1) is useful in distinguishing Merkel cell carcinomas (MCCs) from metastatic small cell carcinomas (SCCs). METHODS: Eleven cases of MCC and 10 of lung SCC were stained for CK20 ...

Subject

Merkel cell carcinoma

Thyroid Transcription Factor 1

Cytokeratin

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