In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure

L. Smith, Robert; F. RUSK, SCOTT; Ellison, B.; Wessells, P.; Tsuchiya, Kiichiro; R. Carter, D.; E. Caler, W.; J. Sandell, Linda; J. Schurman, David

doi:10.1002/jor.1100140110

Public

In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure

Published in Journal of Orthopaedic Research® • Jan 1, 1996

Authors:

Robert L. Smith

SCOTT F. RUSK

B. Ellison

Abstract

This study tested the effects of hydrostatic pressure (10 MPa) on adult articular chondrocyte mRNA and extracellular matrix synthesis in vitro. High density primary cultures of bovine chondrocytes were exposed to hydrostatic pressure applied intermittently at 1 Hz or constantly for 4 hours in serum-...

Subject

Aggrecan

Chondrocyte

Hydrostatic pressure

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