Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.

A Tucker, Budd; Park, In-Hyun; D Qi, Sara; J Klassen, Henry; Jiang, Caihui; Yao, Jing; Redenti, Stephen; Q Daley, George; J Young, Michael

doi:10.1371/journal.pone.0018992

Public

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.

Shared by NobleBlocks on Apr 29, 2011 • 12:00 AM UTC

Authors:

Budd A Tucker

In-Hyun Park

Sara D Qi

Abstract

This study was designed to determine whether adult mouse induced pluripotent stem cells (iPSCs), could be used to produce retinal precursors and subsequently photoreceptor cells for retinal transplantation to restore retinal function in degenerative hosts. iPSCs were generated using adult dsRed mous...

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