Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine–dihydropyridine hybrid molecule

Núñez-Figueredo, Yanier; Ochoa, Estael; Verdecia-Reyes, Yamila; Carrillo Domínguez, Carmen; Lagarto Parra, Alicia; Ramírez-Sánchez, Jeney; Delgado, René; Porto Verdecia, Marlene; L. Pardo‐Andreu, Gilberto

doi:10.1179/1743132813y.0000000216

Public

Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine–dihydropyridine hybrid molecule

Published in Neurological Research • May 8, 2013

Authors:

Yanier Núñez-Figueredo

Estael Ochoa

Yamila Verdecia-Reyes

Abstract

OBJECTIVES: The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20...

Subject

Anxiolytic

Benzodiazepine

Anticonvulsant

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