In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions

Agostinis, Chiara; Biffi, Stefania; Garrovo, Chiara; Durigutto, Paolo; Lorenzon, Andrea; Bek, Alpan; Bulla, Roberta; Grossi, C.; Orietta Borghi, María; Luigi Meroni, Pier; Tedesco, Francesco

doi:10.1182/blood-2011-01-333617

Public

In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions

Published in Blood • Jul 26, 2011

Authors:

Chiara Agostinis

Stefania Biffi

Chiara Garrovo

Abstract

In vitro studies have documented β2 glycoprotein I (β2GPI) binding to endothelial cells (ECs) and trophoblast using antiphospholipid antibodies. The in vivo binding of β2GPI to these cells and the conditions that favor their interaction have not been investigated. We analyzed the in vivo distributio...

Subject

In vivo

Trophoblast

Biology

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