Volumetric brain changes in females with fragile X-associated tremor/ataxia syndrome (FXTAS).

JS, Adams; PE, Adams; D, Nguyen; JA, Brunberg; F, Tassone; W, Zhang; K, Koldewyn; SM, Rivera; J, Grigsby; L, Zhang; C, DeCarli; PJ, Hagerman; RJ, Hagerman

doi:10.1212/01.wnl.0000269781.10417.7b

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Volumetric brain changes in females with fragile X-associated tremor/ataxia syndrome (FXTAS).

Shared by NobleBlocks on Aug 1, 2007 • 12:00 AM UTC

Authors:

Adams JS

Adams PE

Nguyen D

Abstract

Background Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder occurring in male and rare female carriers of a premutation expansion (55 to 200 CGG repeats) of the fragile X mental retardation 1 (FMR1) gene.Methods Volumetric MRI studies, clinical staging, ...

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