Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Polazzi, Elisabetta; Mengoni, Ilaria; Caprini, Marco; Peña‐Altamira, Emiliano; Kurtys, Ewelina; Monti, Barbara

doi:10.1159/000337115

Public

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Published in Neurosignals • May 9, 2012

Authors:

Elisabetta Polazzi

Ilaria Mengoni

Marco Caprini

Abstract

Microglial-neuronal interactions are essential for brain physiopathology. In this framework, recent data have changed the concept of microglia from essentially macrophagic cells to crucial elements in maintaining neuronal homeostasis and function through the release of neuroprotective molecules. Usi...

Subject

Superoxide dismutase

Chemistry

Autocrine signalling

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