Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: Antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus

Amoura, Zahir; Koutouzov, Sophie; Chabre, Henri; Cacoub, P.; Amoura, Isabelle; Musset, Lucile; Bach, Jean‐François; Piette, Jean-Charles

doi:10.1002/1529-0131(200001)43:1<76::aid-anr10>3.0.co;2-i

Public

Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: Antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus

Published in Arthritis & Rheumatism • Jan 1, 2000

Authors:

Zahir Amoura

Sophie Koutouzov

Henri Chabre

Abstract

OBJECTIVE: To study the frequency and disease specificity of antinucleosome antibody reactivity in diverse connective tissue diseases (CTD), and to determine factors, such as antibody subclass, that may influence the pathogenicity of these antibodies in relation to disease activity. METHODS: IgG and...

Subject

Mixed connective tissue disease

Immunology

Medicine

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