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An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

Published in Science • Oct 3, 2014
Authors:
Hans Clevers
,
Kyle M. Loh
,
Roel Nusse

Abstract

Controlling stem cells and their niches Adult organs such as the intestines and skin continually renew themselves every few days or weeks. In several mammalian tissues, this renewal relies on Wnt signaling. Clevers et al. review this crucial role in stem cell self renewal. Wnt plays a pivotal role i...

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