SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates

Schmidt, Bernd; Liebenberg, Volker; Dietrich, Dimo; Schlegel, Thomas; Kneip, Christoph; Seegebarth, Anke; Flemming, Nadja; Seemann, Stefanie; Distler, Jürgen; Lewin, Jörn; Tetzner, Reimo; Weickmann, Sabine; Wille, Ulrike; Liloglou, Triantafillos; Y. Raji, Olaide; Walshaw, Martin; Fleischhacker, Michael; Witt, Christian; K. Field, John

doi:10.1186/1471-2407-10-600

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SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates

Published in BMC Cancer • Nov 3, 2010

Authors:

Bernd Schmidt

Volker Liebenberg

Dimo Dietrich

Abstract

BACKGROUND: This study aimed to show that SHOX2 DNA methylation is a tumor marker in patients with suspected lung cancer by using bronchial fluid aspirated during bronchoscopy. Such a biomarker would be clinically valuable, especially when, following the first bronchoscopy, a final diagnosis cannot ...

Subject

Medicine

Lung cancer

DNA methylation

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