Risk Stratification in the Long-QT Syndrome

G. Priori, Silvia; J. Schwartz, Peter; Napolitano, Carlo; Bloise, Raffaella; Ronchetti, E; Grillo, Massimiliano; Vicentini, Alessandro; Spazzolini, Carla; Nastoli, Jannì; Bottelli, Georgia; Folli, Roberta; Cappelletti, Donata

doi:10.1056/nejmoa022147

Public

Risk Stratification in the Long-QT Syndrome

Published in New England Journal of Medicine • May 7, 2003

Authors:

Silvia G. Priori

Peter J. Schwartz

Carlo Napolitano

Abstract

BACKGROUND: Mutations in potassium-channel genes KCNQ1 (LQT1 locus) and KCNH2 (LQT2 locus) and the sodium-channel gene SCN5A (LQT3 locus) are the most common causes of the long-QT syndrome. We stratified risk according to the genotype, in conjunction with other clinical variables such as sex and the...

Subject

Long QT syndrome

Locus (genetics)

QT interval

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