Traditional Chinese medication Tongxinluo dose-dependently enhances stability of vulnerable plaques: a comparison with a high-dose simvastatin therapy

Zhang, Lei; Liu, Yan; Ting Lu, Xiao; Wu, Yi; Zhang, Cheng; Ping Ji, Xiao; Wang, Rong; Xi Liu, Chun; Feng, Jin; Jiang, Hong; Xu, Xin; Zhao, Yu; Zhang, Yun

doi:10.1152/ajpheart.00208.2009

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Traditional Chinese medication Tongxinluo dose-dependently enhances stability of vulnerable plaques: a comparison with a high-dose simvastatin therapy

Published in American Journal of Physiology-Heart and Circulatory Physiology • Oct 3, 2009

Authors:

Lei Zhang

Yan Liu

Xiao Ting Lu

Abstract

This study was carried out to test the hypothesis that Tongxinluo (TXL) as a Chinese herbal medicine enhances stability of vulnerable plaque dose dependently via lipid-lowering and anti-inflammation effects, similar to a high-dose simvastatin therapy. After abdominal aortic balloon injury, 75 rabbit...

Subject

Simvastatin

Medicine

Vulnerable plaque

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