Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL‐PET study

Whone, Alan; L. Watts, Ray; Jon Stoessl, A.; R. Davis, Margaret; N. Reske, Sven; Nahmias, Claude; E. Lang, Anthony; Rascol, Olivier; João Ribeiro, Maria; Rémy, Philippe; Poewe, Werner; A. Hauser, Robert; J. Brooks, David; Study Group, REAL‐PET

doi:10.1002/ana.10609

Public

Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL‐PET study

Published in Annals of Neurology • Jun 25, 2003

Authors:

Alan Whone

Ray L. Watts

A. Jon Stoessl

Abstract

Preclinical studies suggest ropinirole (a D2/D3 dopamine agonist) may be neuroprotective in Parkinson's disease (PD), and a pilot clinical study using (18)F-dopa positron emission tomography (PET) suggested a slower loss of striatal dopamine storage with ropinirole compared with levodopa. This prosp...

Subject

Ropinirole

Levodopa

Putamen

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