Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species

Setsukinai, Ken‐ichi; Urano, Yasuteru; Kakinuma, Katsuko; J. Majima, Hideyuki; Nagano, Tetsuo

doi:10.1074/jbc.m209264200

Public

Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species

Published in Journal of Biological Chemistry • Jan 1, 2003

Authors:

Ken‐ichi Setsukinai

Yasuteru Urano

Katsuko Kakinuma

Abstract

We designed and synthesized 2-[6-(4'-hydroxy)phenoxy-3H-xanthen-3-on-9-yl]benzoic acid (HPF) and 2- [6-(4'-amino)phenoxy-3H-xanthen-3-on-9-yl]benzoic acid (APF) as novel fluorescence probes to detect selectively highly reactive oxygen species (hROS) such as hydroxyl radical (*OH) and reactive interm...

Subject

Fluorescence

Reactive oxygen species

Biology

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