Identification of a phosphatidylinositol‐4,5‐bisphosphate‐binding domain in the N‐terminal region of ezrin

Niggli, Verena; Andréoli, Christophe; Roy, Christian; Mangeat, Paul

doi:10.1016/0014-5793(95)01270-1

Public

Identification of a phosphatidylinositol‐4,5‐bisphosphate‐binding domain in the N‐terminal region of ezrin

Published in FEBS Letters • Dec 4, 1995

Authors:

Verena Niggli

Christophe Andréoli

Christian Roy

Abstract

Purified human recombinant ezrin cosediments with large liposomes containing phosphatidylserine (PS). This interaction is optimal at low ionic strength. At physiological ionic strength (130 mM KCl) ezrin interacts strongly with liposomes containing > or = 5% phosphatidylinositol-4,5-bisphosphate (PI...

Subject

Phosphatidylinositol

Liposome

Ezrin

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