SLAF-seq: An Efficient Method of Large-Scale De Novo SNP Discovery and Genotyping Using High-Throughput Sequencing

Sun, Xiaowen; Liu, Dongyuan; Zhang, Xiaofeng; Li, Wenbin; Liu, Hui; Hong, Weiguo; Jiang, Chuanbei; Guan, Ning; Ma, Chouxian; Zeng, Huaping; Xu, Chunhua; Song, Jun; Huang, Long; Wang, Chunmei; Shi, Junjie; Wang, Rui; Zheng, Xianhu; Lu, Cuiyun; Wang, Xiaowu; Zheng, Hongkun

doi:10.1371/journal.pone.0058700

Public

SLAF-seq: An Efficient Method of Large-Scale De Novo SNP Discovery and Genotyping Using High-Throughput Sequencing

Published in PLoS ONE • Mar 19, 2013

Authors:

Xiaowen Sun

Dongyuan Liu

Xiaofeng Zhang

Abstract

Large-scale genotyping plays an important role in genetic association studies. It has provided new opportunities for gene discovery, especially when combined with high-throughput sequencing technologies. Here, we report an efficient solution for large-scale genotyping. We call it specific-locus ampl...

Subject

Genotyping

Biology

Deep sequencing

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