Three new long-acting converting-enzyme inhibitors: relationship between plasma converting-enzyme activity and response to angiotensin I.

J, Biollaz; M, Burnier; GA, Turini; DB, Brunner; M, Porchet; HJ, Gomez; KH, Jones; F, Ferber; WB, Abrams; H, Gavras; HR, Brunner

doi:10.1038/clpt.1981.92

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Three new long-acting converting-enzyme inhibitors: relationship between plasma converting-enzyme activity and response to angiotensin I.

Shared by NobleBlocks on May 1, 1981 • 12:00 AM UTC

Authors:

Biollaz J

Burnier M

Turini GA

Abstract

Three new angiotensin converting-enzyme inhibitors were given orally to 20 men in single doses ranging from 1.25 to 40 mg. Two of them induced comparable marked inhibition of both the blood pressure response to exogenous angiotensin I and plasma converting-enzyme activity. Onset of action was relati...

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