Structural abnormalities in cortical volume, thickness, and surface area in 22q11.2 microdeletion syndrome: Relationship with psychotic symptoms

Jalbrzikowski, Maria; K. Jonas, Rachel; Şentürk, Damla; Patel, Arati; Chow, Carolyn; F. Green, Michael; E. Bearden, Carrie

doi:10.1016/j.nicl.2013.09.013

Public

Structural abnormalities in cortical volume, thickness, and surface area in 22q11.2 microdeletion syndrome: Relationship with psychotic symptoms

Published in NeuroImage Clinical • Jan 1, 2013

Authors:

Maria Jalbrzikowski

Rachel K. Jonas

Damla Şentürk

Abstract

INTRODUCTION: 22q11.2 deletion syndrome (22q11DS) represents one of the largest known genetic risk factors for psychosis, yet the neurobiological mechanisms underlying symptom development are not well understood. Here we conducted a cross-sectional study of 22q11DS to decompose cortical volume into ...

Subject

Orbitofrontal cortex

Cuneus

Postcentral gyrus

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