Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study

Cuzick, Jack; P. Swanson, Gregory; Fisher, Gabrielle; R. Brothman, Arthur; M. Berney, Daniel; Reid, Julia; Mesher, David; O. Speights, V.; Stankiewicz, Elzbieta; S. Foster, Christopher; Møller, Henrik; T. Scardino, Peter; D Warren, Jorja; Park, Jimmy; Younus, Adib; D. Flake, Darl; Wagner, Susanne; Gutin, Alexander; S. Lanchbury, Jerry; Stone, Steven

doi:10.1016/s1470-2045(10)70295-3

Public

Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study

Published in The Lancet Oncology • Feb 9, 2011

Authors:

Jack Cuzick

Gregory P. Swanson

Gabrielle Fisher

Abstract

BACKGROUND: Optimum management of clinically localised prostate cancer presents unique challenges because of the highly variable and often indolent natural history of the disease. To predict disease aggressiveness, clinicians combine clinical variables to create prognostic models, but the models hav...

Subject

Prostatectomy

Prostate cancer

Medicine

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