Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

J. Prockop, Darwin; Youn Oh, Joo

doi:10.1038/mt.2011.211

Public

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

Published in Molecular Therapy • Oct 18, 2011

Authors:

Darwin J. Prockop

Joo Youn Oh

Abstract

Recent observations have demonstrated that one of the functions of mesenchymal stem/stromal cells (MSCs) is to serve as guardians against excessive inflammatory responses. One mode of action of the cells is that they are activated to express the interleukin (IL)-1 receptor antagonist. A second mode ...

Subject

Mesenchymal stem cell

Inflammation

Stromal cell

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