Antinociceptive Activities and the Mechanisms of Anti‐Inflammation of Asiatic Acid in Mice

Huang, Shyh‐Shyun; Chiu, Chuan‐Sung; Chen, Hsien‐Jung; Hou, Wen‐Chi; Sheu, Ming‐Jyh; Lin, Ying-Chih; Shie, Pei-Hsin; Huang, Guan‐Jhong

doi:10.1155/2011/895857

Public

Antinociceptive Activities and the Mechanisms of Anti‐Inflammation of Asiatic Acid in Mice

Published in Evidence-based Complementary and Alternative Medicine • Jan 1, 2011

Authors:

Shyh‐Shyun Huang

Chuan‐Sung Chiu

Hsien‐Jung Chen

Abstract

Asiatic acid (AA), a pentacyclic triterpene compound in the medicinal plant Centella asiatica, was evaluated for antinociceptive and anti-inflammatory effects. Treatment of male ICR mice with AA significantly inhibited the numbers of acetic acid-induced writhing responses and the formalin-induced pa...

Subject

Pharmacology

Superoxide dismutase

Chemistry

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