Altered Insulin Secretory Responses to Glucose in Diabetic and Nondiabetic Subjects With Mutations in the Diabetes Susceptibility Gene MODY3 on Chromosome 12

M. Byrne, M.; Sturis, Jeppe; Menzel, Stephan; Yamagata, Kazuya; S. Fajans, Stefan; J. Dronsfield, M.; C. Bain, Stephen; T. Hattersley, Andrew; Velho, Gilberto; Froguel, Philippe; I. Bell, Graeme; S. Polonsky, Kenneth

doi:10.2337/diab.45.11.1503

Public

Altered Insulin Secretory Responses to Glucose in Diabetic and Nondiabetic Subjects With Mutations in the Diabetes Susceptibility Gene MODY3 on Chromosome 12

Published in Diabetes • Nov 1, 1996

Authors:

M. M. Byrne

Jeppe Sturis

Stephan Menzel

Abstract

One form of maturity-onset diabetes of the young (MODY) results from mutations in a gene, designated MODY3, located on chromosome 12 in band q24. The present study was undertaken to define the interactions between glucose and insulin secretion rate (ISR) in subjects with mutations in MODY3. Of the 1...

Subject

Internal medicine

Endocrinology

Diabetes mellitus

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