<i>COMT</i>: A common susceptibility gene in bipolar disorder and schizophrenia

Shifman, Sagiv; Bronstein, Michal; Sternfeld, Meira; Pisanté, Anne; Weizman, Avraham; Reznik, Ilya; Spivak, Baruch; Grisaru, Nimrod; Karp, Leon; Schiffer, Richard; Kotler, Moshe; D. Strous, Rael; Swartz‐Vanetik, Marnina; Y. Knobler, Haim; Shinar, Eilat; Yakir, Benjamin; B. Zak, Naomi; Darvasi, Ariel

doi:10.1002/ajmg.b.30032

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COMT: A common susceptibility gene in bipolar disorder and schizophrenia

Shared by NobleBlocks on Apr 22, 2004 • 12:00 AM UTC

Authors:

Sagiv Shifman

Michal Bronstein

Meira Sternfeld

Abstract

Abstract A variety of psychiatric illnesses, including schizophrenia and bipolar disorder, have been reported in patients with microdeletion on chromosome 22q11—a region which includes the catechol‐O‐methyltransferase ( COMT ) gene. The variety of psychiatric manifestations in patients with the 22q1...

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