Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

H. Abuznait, Alaa; Qosa, Hisham; A. Busnena, Belnaser; A. El Sayed, Khalid; Kaddoumi, Amal

doi:10.1021/cn400024q

Public

Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

Published in ACS Chemical Neuroscience • Feb 15, 2013

Authors:

Alaa H. Abuznait

Hisham Qosa

Belnaser A. Busnena

Abstract

Oleocanthal, a phenolic component of extra-virgin olive oil, has been recently linked to reduced risk of Alzheimer's disease (AD), a neurodegenerative disease that is characterized by accumulation of β-amyloid (Aβ) and tau proteins in the brain. However, the mechanism by which oleocanthal exerts its...

Subject

Neuroprotection

In vivo

Pharmacology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!