IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection

Lagging, Martin; I. Romero, Ana; Westin, Johan; Norkrans, Gunnar; P. Dhillon, Amar; Pawlotsky, Jean–Michel; Zeuzem, Stefan; Wagner, Michael; Negro, Francesco; W. Schalm, Solko; L. Haagmans, Bart; Ferrari, Carlo; Missale, Gabriele; U. Neumann, Avidan; Verheij‐Hart, Elke; Hellstrand, Kristoffer

doi:10.1002/hep.21407

Public

IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection

Published in Hepatology • Nov 28, 2006

Authors:

Martin Lagging

Ana I. Romero

Johan Westin

Abstract

Plasma from 173 patients with HCV genotype 1 infection was analyzed for IP-10 levels prior to treatment with pegylated interferon-alpha-2a and ribavirin. Significantly lower IP-10 levels were observed in patients achieving a rapid viral response (RVR) (P or = 25 kg/m2 (P = .004) and with baseline vi...

Subject

Viral load

Ribavirin

Internal medicine

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