Chondrocyte cell death and intracellular distribution of COMP and type IX collagen in the pseudoachondroplasia growth plate.

JT, Hecht; O, Makitie; E, Hayes; R, Haynes; M, Susic; D, Montufar-Solis; PJ, Duke; WG, Cole

doi:10.1016/j.orthres.2003.11.010

Public

Chondrocyte cell death and intracellular distribution of COMP and type IX collagen in the pseudoachondroplasia growth plate.

Shared by NobleBlocks on Jul 1, 2004 • 12:00 AM UTC

Authors:

Hecht JT

Makitie O

Hayes E

Abstract

Cartilage oligomeric matrix protein (COMP) is a large extracellular matrix protein expressed in cartilage, ligament and tendon. Mutations in the COMP gene cause two dominantly inherited skeletal dysplasias, pseudoachondroplasia (PSACH) and Multiple Epiphyseal Dysplasia (MED/EDM1). We report on a nov...

Discussions