K13-Propeller Polymorphisms in Plasmodium falciparum Parasites From Sub-Saharan Africa

Kamau, Edwin; Campino, Susana; Amenga–Etego, Lucas; Drury, Eleanor; S. Ishengoma, Deus; J. Johnson, Kimberly; Mumba, D.; Kekre, Mihir; Yavo, William; G. Mead, Daniel; Karine Bouyou-Akotet, Marielle; O. Apinjoh, Tobias; Golassa, Lemu; Randrianarivelojosia, Milijaona; M. Andagalu, Ben; Maïga‐Ascofaré, Oumou; Amambua‐Ngwa, Alfred; Tindana, Paulina; Ghansah, Anita; MacInnis, Bronwyn; Kwiatkowski, Dominic; Djimdé, Abdoulaye

doi:10.1093/infdis/jiu608

Public

K13-Propeller Polymorphisms in Plasmodium falciparum Parasites From Sub-Saharan Africa

Published in The Journal of Infectious Diseases • Nov 2, 2014

Authors:

Edwin Kamau

Susana Campino

Lucas Amenga–Etego

Abstract

Mutations in the Plasmodium falciparum K13-propeller domain have recently been shown to be important determinants of artemisinin resistance in Southeast Asia. This study investigated the prevalence of K13-propeller polymorphisms across sub-Saharan Africa. A total of 1212 P. falciparum samples collec...

Subject

Plasmodium falciparum

Nonsynonymous substitution

Malaria

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