Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphoma

Espinet, Blanca; Salaverría, Itziar; Beà, Sı́lvia; Ruiz‐Xivillé, Neus; Balagué, Olga; Salido, Marta; Costa, Dolors; Carreras, Joaquim; E. Rodríguez‐Vicente, Ana; Luis Garcı́a, Juan; María Hernández‐Rivas, Jesús; José Calasanz, Marı́a; Siebert, Reiner; Ferrer, Ana; Salar, Antonio; Carrió, Ana; Polo, Natividad; A. García‐Marco, José; Domingo, Alícia; González‐Barca, Eva; Romagosa, V.; Marugán, Isabel; López‐Guillermo, Armando; Millá, Fuensanta; Luís Mate, José; Luño, Elisa; Sanzo, Carmen; Collado, Rosa; Oliver, Isabel; Monzó, Sebastià; Palacı́n, Antonio; González, Teresa; Sant, Francesc; Salinas, Ramón; T. Ardañaz, María; Font, Llorenç; Escoda, Lourdes; Florensa, Lourdes; Serrano, Sergi; Campo, Elı́as; Solé, Françesc

doi:10.1002/gcc.20754

Public

Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphoma

Published in Genes Chromosomes and Cancer • Feb 8, 2010

Authors:

Blanca Espinet

Itziar Salaverría

Sı́lvia Beà

Abstract

Mantle cell lymphoma (MCL) is a mature B-cell neoplasm with an aggressive behavior, characterized by the t(11;14)(q13;q32). Several secondary genetic abnormalities with a potential role in the oncogenic process have been described. Studies of large MCL series using conventional cytogenetics, and cor...

Subject

Cytogenetics

Blastoid

Biology

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