Phenotypically distinct subsets of CD4<sup>+</sup> T cells induce or protect from chronic intestinal inflammation in C. B-17 <i>scid</i> mice

Powrie, Flona; W. Leach, Michael; Mauze, Smita; Barcomb Caddie, Linda; L. Coffman, Robert

doi:10.1093/intimm/5.11.1461

Public

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

Published in International Immunology • Jan 1, 1993

Authors:

Flona Powrie

Michael W. Leach

Smita Mauze

Abstract

CD4+ T cells in the mouse can be subdivided into two fractions based on the level of expression of the CD45RB determinant. Previous studies have shown that these subsets are functionally distinct. We have further characterized the properties of these subpopulations in vivo by injecting them into C. ...

Subject

Wasting

Population

Immunology

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