Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by <i>Staphylococcus aureus</i>

G. Fowler, Vance; W. Boucher, Helen; Ralph Corey, G.; Abrutyn, Elías; W. Karchmer, Adolf; E. Rupp, Mark; P. Levine, Donald; F. Chambers, Henry; P. Tally, Francis; Vigliani, Gloria; H. Cabell, Christopher; S. Link, Arthur; Demeyer, Ignace; G. Filler, Scott; Zervos, Marcus; Cook, Paul; Parsonnet, Jeffrey; Bernstein, Jack; Price, Connie; N. Forrest, Graeme; Fätkenheuer, Gerd; Gareca, Marcelo; J. Rehm, Susan; Brodt, H.-R.; D. Tice, Alan; E. Cosgrove, Sara

doi:10.1056/nejmoa053783

Public

Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by Staphylococcus aureus

Published in New England Journal of Medicine • Aug 16, 2006

Authors:

Vance G. Fowler

Helen W. Boucher

G. Ralph Corey

Abstract

BACKGROUND: Alternative therapies for Staphylococcus aureus bacteremia and endocarditis are needed. METHODS: We randomly assigned 124 patients with S. aureus bacteremia with or without endocarditis to receive 6 mg of daptomycin intravenously per kilogram of body weight daily and 122 to receive initi...

Subject

Daptomycin

Medicine

Bacteremia

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