Molecular Cloning and Characterization of the Human and Mouse UDP-Glucose Dehydrogenase Genes

P. Spicer, Andrew; A. Kaback, Lee; J. Smith, Terry; F. Seldin, Michael

doi:10.1074/jbc.273.39.25117

Public

Molecular Cloning and Characterization of the Human and Mouse UDP-Glucose Dehydrogenase Genes

Published in Journal of Biological Chemistry • Sep 1, 1998

Authors:

Andrew P. Spicer

Lee A. Kaback

Terry J. Smith

Abstract

The enzyme UDP-glucose dehydrogenase (Udpgdh) (EC 1.1.1.22) converts UDP-glucose to UDP-glucuronate, a critical component of the glycosaminoglycans, hyaluronan, chondroitin sulfate, and heparan sulfate. Although Udpgdh is a comparatively well characterized enzyme, no vertebrate genes encoding this e...

Subject

Biology

Glucuronate

Molecular biology

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