Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes.

P Spicer, A; A Kaback, L; J Smith, T; F Seldin, M

doi:10.1074/jbc.273.39.25117

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Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes.

Shared by NobleBlocks on Sep 25, 1998 • 12:00 AM UTC

Authors:

A P Spicer

L A Kaback

T J Smith

Abstract

The enzyme UDP-glucose dehydrogenase (Udpgdh) (EC 1.1.1.22) converts UDP-glucose to UDP-glucuronate, a critical component of the glycosaminoglycans, hyaluronan, chondroitin sulfate, and heparan sulfate. Although Udpgdh is a comparatively well characterized enzyme, no vertebrate genes encoding this e...

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