Na-K-2Cl cotransporter inhibition impairs human lung cellular proliferation.
Published in American journal of physiology. Lung cellular and molecular physiology • Sep 1, 2004
Authors:,,
Lynn M Iwamoto
Naomi Fujiwara
Kenneth T Nakamura
Abstract
The widespread presence of the Na-K-2Cl (NKCC) cotransporter protein suggests that chronic administration of inhibitors may result in adverse effects. Inhibition of the NKCC cotransporter by loop diuretics is felt to underlie the diuretic and the pulmonary smooth muscle relaxant effects of this drug...
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