The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies.

Sebbag, Mireille; Simon, Michel; Vincent, Christian; Masson-Bessière, Christine; Girbal, E; J Durieux, J; Serre, Guy

doi:10.1172/jci117969

Public

The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies.

Published in Journal of Clinical Investigation • Jun 1, 1995

Authors:

Mireille Sebbag

Michel Simon

Christian Vincent

Abstract

The so-called antikeratin antibodies (AKA) and the antiperinuclear factor (APF) are the most specific serological markers of RA. Using indirect immunofluorescence, AKA label the stratum corneum of various cornified epithelia and APF the keratohyalin granules of human buccal mucosa epithelium. We rec...

Subject

Filaggrin

Autoantibody

Cicatricial pemphigoid

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