Pathophysiological Mechanisms of Brain Damage from Status Epilepticus

G. Wasterlain, Claude; G. Fujikawa, Denson; Penix, LaRoy; Sankar, Raman

doi:10.1111/j.1528-1157.1993.tb05905.x

Public

Pathophysiological Mechanisms of Brain Damage from Status Epilepticus

Published in Epilepsia • Jan 1, 1993

Authors:

Claude G. Wasterlain

Denson G. Fujikawa

LaRoy Penix

Abstract

Human status epilepticus (SE) is consistently associated with cognitive problems, and with widespread neuronal necrosis in hippocampus and other brain regions. In animal models, convulsive SE causes extensive neuronal necrosis. Nonconvulsive SE in adult animals also leads to widespread neuronal necr...

Subject

Status epilepticus

Pathophysiology

Neuroscience

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