Human Immunodeficiency Virus <i>nef</i> Signature Sequences Are Associated with Pulmonary Hypertension

Almodóvar, Sharilyn; Knight, Rob; A. Allshouse, Amanda; C. Roemer, Sarah; Lozupone, Catherine; McDonald, Daniel; Widmann, Jeremy; F. Voelkel, Norbert; J Shelton, Robert; Suárez, Edu; W. Hammer, Kenneth; Goujard, Cécile; Petrosillo, Nicola; Simonneau, Gérald; Y. Hsue, Priscilla; Humbert, Marc; C. Flores, Sonia

doi:10.1089/aid.2011.0021

Public

Human Immunodeficiency Virus nef Signature Sequences Are Associated with Pulmonary Hypertension

Published in AIDS Research and Human Retroviruses • Nov 9, 2011

Authors:

Sharilyn Almodóvar

Rob Knight

Amanda A. Allshouse

Abstract

Severe pulmonary hypertension (PH) associated with vascular remodeling is a long-term complication of HIV infection (HIV-PH) affecting 1/200 infected individuals vs. 1/200,000 frequency in the uninfected population. Factors accounting for increased PH susceptibility in HIV-infected individuals are u...

Subject

Lentivirus

Pathogenesis

Biology

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