Biopsy Neutrophilia, Neutrophil Chemokine and Receptor Gene Expression in Severe Exacerbations of Chronic Obstructive Pulmonary Disease

Qiu, Yusheng; Zhu, Jie; Bandi, Venkata; L. Atmar, Robert; Hattotuwa, Keith; K. Guntupalli, Kay; K. Jeffery, Peter

doi:10.1164/rccm.200208-794oc

Public

Biopsy Neutrophilia, Neutrophil Chemokine and Receptor Gene Expression in Severe Exacerbations of Chronic Obstructive Pulmonary Disease

Published in American Journal of Respiratory and Critical Care Medicine • Jul 14, 2003

Authors:

Yusheng Qiu

Jie Zhu

Venkata Bandi

Abstract

We have applied immunohistology and in situ hybridization to bronchial biopsies of patients with chronic obstructive pulmonary disease (COPD) to examine neutrophil recruitment and to determine neutrophil chemoattractant and CXC receptor (CXCR) 1 and CXCR2 gene expression associated with acute severe...

Subject

Neutrophilia

Medicine

COPD

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