Angiotensin-(1–7) is an endogenous ligand for the G protein-coupled receptor Mas

A.S. Santos, Robson; Cristina Simões e Silva, Ana; Maric, Christine; M. R. Silva, Denise; Machado, R.P.; de Buhr, Insa; Heringer‐Walther, Silvia; Veloso Brant Pinheiro, Sérgio; Teresa Lopes, Myriam; Bäder, Michael; Pereira Mendes, Elizabeth; S. Lemos, Virgı́nia; José Campagnole‐Santos, Maria; Schultheiss, Heinz‐Peter; C. Speth, Robert; Walther, Thomas

doi:10.1073/pnas.1432869100

Public

Angiotensin-(1–7) is an endogenous ligand for the G protein-coupled receptor Mas

Published in Proceedings of the National Academy of Sciences • Jun 26, 2003

Authors:

Robson A.S. Santos

Ana Cristina Simões e Silva

Christine Maric

Abstract

The renin-angiotensin system plays a critical role in blood pressure control and body fluid and electrolyte homeostasis. Besides angiotensin (Ang) II, other Ang peptides, such as Ang III [Ang-(2-8)], Ang IV [Ang-(3-8)], and Ang-(1-7) may also have important biological activities. Ang-(1-7) has becom...

Subject

Angiotensin II

Receptor

Internal medicine

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