CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer.

Wang, Jiayi; Liu, Xiangfan; Wu, Huacheng; Ni, Peihua; Gu, Zhidong; Qiao, Yongxia; Chen, Ning; Sun, Fenyong; Fan, Qishi

doi:10.1093/nar/gkq285

Public

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer.

Shared by NobleBlocks on Sep 1, 2010 • 12:00 AM UTC

Authors:

Jiayi Wang

Xiangfan Liu

Huacheng Wu

Abstract

Long non-coding RNA (lncRNA), highly up-regulated in liver cancer (HULC) plays an important role in tumorigenesis. Depletion of HULC resulted in a significant deregulation of several genes involved in liver cancer. Although up-regulation of HULC expression in hepatocellular carcinoma has been report...

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