Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid Desert<i>Streptomyces</i>sp.

E. Rateb, Mostafa; E. Houssen, Wael; F. F. Arnold, Markus; Abdelrahman, Mostafa; Deng, Hai; Harrison, W.T.A.; K. Okoro, Chinyere; A. Asenjo, Juan; A. Andrews, Bárbara; P. Ferguson, Gail; T. Bull, Alan; Goodfellow, Michael; Ebel, Rainer; Jaspars, Marcel

doi:10.1021/np200320u

Public

Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid DesertStreptomycessp.

Published in Journal of Natural Products • May 9, 2011

Authors:

Mostafa E. Rateb

Wael E. Houssen

Markus F. F. Arnold

Abstract

Streptomyces sp. strain C34, isolated from soil collected in the Chilean hyper-arid Atacama Desert, was cultured on different media, resulting in the isolation and identification of four new ansamycin-type polyketides. The organism was selected for chemical investigation on the basis of a genome-min...

Subject

Escherichia coli

Staphylococcus aureus

Strain (injury)

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