A unique molecular chaperone Cosmc required for activity of the mammalian core 1 β3-galactosyltransferase

Ju, Tongzhong; D. Cummings, Richard

doi:10.1073/pnas.262438199

Public

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 β3-galactosyltransferase

Published in Proceedings of the National Academy of Sciences • Dec 3, 2002

Authors:

Tongzhong Ju

Richard D. Cummings

Abstract

Human core 1 beta3-galactosyltransferase (C1beta3Gal-T) generates the core 1 O-glycan Galbeta1-3GalNAcalpha1-SerThr (T antigen), which is a precursor for many extended O-glycans in animal glycoproteins. We report here that C1beta3Gal-T activity requires expression of a molecular chaperone designated...

Subject

Molecular biology

Biology

Complementary DNA

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!